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The initial doses are primarily intended to improve gastrointestinal tolerance rather than maximize weight loss
Dumping symptoms is triggered by fat as well as carbohydrates in patients operated with Roux-en-Y gastric bypass
Saroglitazar magnesium, a dual PPAR-/ agonist, was designed to have a weaker PPAR- effect to reduce untoward side effects related to PPAR- agonism.(22) Through its PPAR- agonism, saroglitazar increases hepatic oxidation of fatty acids, lowers synthesis and secretion of triglycerides (TGs), and produces favorable changes in circulating lipoproteins
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Additionally, any symptoms that interfere with the ability to fall asleep or stay asleep, leading to significant daytime fatigue or impaired concentration, require professional assessment
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