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In summary, beyond the expected effects on binding to albumin, C-terminal acylation of exendin-4 led to changes in multiple pharmacological parameters relevant to downstream GLP-1R responses
It is deciding what to do, and crucially, what not to do
(2008) 138:226S34S
But this short half-life doesn't tell the full story - the peptide triggers cellular processes (collagen synthesis, wound healing, anti-inflammatory cascades) that continue for days after the peptide itself has cleared
FDA does not pre-approve dietary supplements before they are sold
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