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Clinical studies show: Mounjaro (tirzepatide) can help patients lose up to 22% of their body weight on average over 72 weeks Wegovy (semaglutide) produces an average 17% weight loss after 68 weeks under medical supervision Bariatric surgery such as a gastric sleeve or bypass can sometimes result in up to 70% total body weight loss within 1 to 2 years, but this depends on post-surgery lifestyle choices

During supply issues The FDA permitted the sale of compounded semaglutide when there was a widespread shortage of FDA-approved versions, such as Ozempic and Wegovy