Wegovy and Saxenda, both injectables, are the only GLP-1s FDA-approved for obesity
The paradigm shift that began with EMPA-REG OUTCOME and LEADER has led to SGLT2 inhibitors and GLP-1 RA being recognised not only in international diabetes guidelines, but also as an important consideration for patients with T2D in CVD prevention [28,29,30, 76, 77], HF [133,134,135] and CKD [41, 102] guidelines, where it has been suggested that these agents should be considered early in the course of diabetes management
Extended periods at room temperature degrade the peptide
By slowing digestion and signaling fullness, Semaglutide makes it easier to eat less without constant hunger
Los agonistas del GLP-1 son frmacos diseados para activar los mismos receptores que el GLP-1 natural