Zhang HL, Hu BX, Li ZL, Du T, Shan JL, Ye ZP, et al
By the way, this was discovered by Cynthia Kenyon, and this was back in the '90s
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the goal was to ensure coverage of a wide range of issues and literature including and emphasizing the most classic publications screened by high citations or published by leading scholars
In isolated rat aorta preparations, the peptide produced concentration-dependent vasodilation that was endothelium-dependent and abolished by L-NAME, and co-immunoprecipitation work traced the response to phosphorylation of Src, caveolin-1, and endothelial nitric oxide synthase, with reduced binding between caveolin-1 and eNOS [1]