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This dual-pathway approach also preserves natural GH pulsatility and feedback regulation, which is a significant advantage over direct GH replacement

Also, high levels of insulin can make the ovaries produce more androgens, leading to PCOS symptoms like hirsutism and acne

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*Correspondence: Qing-Rong Xia [email protected] This article was submitted to Mood and Anxiety Disorders, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This distension could potentially stimulate the phrenic nerve or vagus nerve, both of which play roles in the hiccup reflex arc