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Laboratory investigation typically includes comprehensive metabolic panel, magnesium level, creatine kinase (if muscle injury is suspected), and possibly vitamin D level
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If fasting glucose trends upward or HbA1c increases, this signals developing insulin resistance
They should include personalized care, not just medication access
In mice, GLP-1 agonists reduced atherosclerosis even when weight loss was matched, supporting the weight-loss-independent mechanism
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