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It is mediated by the binding of protein antigens to IgE antibodies on dermal mast cells, triggering rapid degranulation and the release of histamine, leukotrienes, prostaglandins, and other vasoactive mediators [33, 34]

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Liver Res 5:4552 Woodhead JL, Yang K, Oldach D, MacLauchlin C, Fernandes P, Watkins PB et al (2019) Analyzing the mechanisms behind macrolide antibiotic-induced liver injury using quantitative systems toxicology modeling

The most common reactions include transient digestive upset (nausea, vomiting, stomach cramps, or diarrhea), a mild fishy body odor, headache, or soreness and redness where the injection is given

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