semaglutide .25 weight loss reddit M/43/5'11" [309lbs > 193lbs = 116lbs] | 9 months Potential New GLP-1 Side Effects

Presented for research literature review only Pfffle R et al

Most patients notice appetite suppression within 35 days of their first 0.25 mg dose, though full effect builds over the first 23 weeks

5 Market outlook Eli Lillys oral non-peptide GLP-1RA orforglipron is advancing through the ACHIEVE Phase III program, with Lilly signaling regulatory submissions for obesity in 2025 and type 2 diabetes in 2026, following positive results from both Phase 2 obesity (GZGI) and Phase 3 T2DM (ACHIEVE-1) trials

First, for patients with an active supply of AOM tirzepatide and AOM semaglutide, we calculated the percentage who switched to a different GLP-1 RA

The CV protection indication for semaglutide stems from a meta-analysis published in 2021 (Lancet Diabetes Endocrinol 2021 Oct;9(10):653-662)