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Hypoglycaemia risk is the primary safety consideration, along with potential joint swelling and carpal tunnel effects at higher doses
93,101 Stubbs et al also described a negative correlation between serum TMAO concentration and estimated GFR (eGFR)
This study presents the concept of the polarity index, which measures how antidepressant versus antimanic a drug is in bipolar disorder prophylaxis
Correia et al
The key here is efficiency
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