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Diabetes 37:14531469 Kruman I, Guo Q, Mattson MP (1998) Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells

Some patients require a short course to restore levels, while others benefit from regular maintenance injections (for example, monthly or quarterly)

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[3] Signs, symptoms and complications [edit] Vitamin B 12 deficiency appears slowly and worsens over time, and can often be confused with other conditions