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Further isotope labeling experiments confirmed that upon GGCT overexpression, Gln is preferentially shunted to the GSH synthesis pathway, with a significantly reduced proportion entering the TCA cycle
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All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA)
Scientists utilize cellbased assays and in vitro systems to evaluate binding properties, structural stability, and signaling behavior under controlled conditions
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