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Among the most promising non-incretin receptor targets are amylin (Amy) receptors (AMYRs), supported by data from phase I and phase II clinical trials showing efficacy of the long-acting amylin and calcitonin receptor agonist, cagrilinitide (Cagri), both as monotherapy 2,3 and in combination with the selective GLP-1R agonist, semaglutide 4,5
The 2024 NICE guideline on B12 deficiency in over-16s is built around identifying and treating the cause, not just topping up the number
So I want to be very clear about my stance on this
Presented for research literature review only Ma K et al
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