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Currently, the U.S

Additionally, new or worsening constipation accompanied by unexplained weight loss (beyond expected therapeutic weight reduction), persistent changes in stool caliber, or alternating constipation and diarrhea warrants evaluation to exclude structural or neoplastic causes, particularly in patients age 45 or older or those with family history of colorectal cancer

Similarly, Liu et al

That general rule still applies, but starting July 1, 2026, the Centers for Medicare & Medicaid Services (CMS) is launching a short-term demonstration called the Medicare GLP-1 Bridge , which changes the picture for eligible beneficiaries through the end of the year

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