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Infiltrating T cells were found in the vitiligo skin surrounding the lesions, and circulating autoantibodies recognizing MCs antigens and autoreactive cytotoxic T lymphocytes (CTLs) were detected in the sera of a large number of vitiligo patients [26]

9C) showed strong representation of pathogenic Firmicutes lineages (Erysipelotrichaceae, Peptostreptococcales-Tissierellales, Christensenellaceae) and severe reduction of Bacteroidota in the VPA-ASD model

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The presence of this extracellular lactate promotes the polarization of macrophages towards a resolution/repair phenotype, which contributes to tissue remodeling and immune tolerance [88] (Fig

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