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The precise mechanisms by which amlodipine relieves angina have not been fully delineated, but are thought to include the following: Exertional Angina In patients with exertional angina, amlodipine besylate reduces the total peripheral resistance (afterload) against which the heart works and reduces the rate pressure product, and thus myocardial oxygen demand, at any given level of exercise
(2003) reported that the sulfinic form, produced under high levels of H 2 O 2 , was reduced to the catalytically active thiol form
Hauser RA, Lyons KE, McClain T, Carter S, Perlmutter D
Front Immunol 11:322 Nayak D, Adiga D, Khan NG, Rai PS, Dsouza HS, Chakrabarty S et al (2022) Impact of bisphenol A on structure and function of mitochondria: a critical review
The cellular redox state is involved in regulating tyrosine phosphatase activity through the reversible oxidation of catalytic cysteine to sulfenic/sulfinic acid (86)
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