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doi: 10.3389/fimmu.2025.1732718 Received 26 October 2025 Revised 19 November 2025 Accepted 26 November 2025 Published 12 December 2025 Volume 16 - 2025 Edited by Maria Pini, Alira Health, France Reviewed by Ebrahim Mazloomi, Urmia University of Medical Sciences, Iran Saloni Gupta, Indian Institute of Technology Roorkee, India Updates Copyright 2025 Ji, Li, Yao, Sun, Yi, Shen, Chen and Sun