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While we focus on cardiac hypertrophy, the SIRT2-Rheb-mTORC1 regulation axis may also be relevant for other human diseases

Any excess is typically excreted in the urine, lowering the risk of toxicity

Due to its potency, hydroquinone is often prescribed for: Severe melasma Stubborn hyperpigmentation Post-inflammatory dark patches However, hydroquinone is prescription-only in many countries and restricted or banned in others because of safety concerns related to long-term or improper use

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