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In addition to reversing the expression of the COPD gene, it was found that GHK is capable of activating the opposite pathway, TNF-beta
While not commonly reported with Pendulum specifically, people sensitive to gut-brain interactions may notice temporary mood fluctuations during the adjustment period
Those facts were confirmed in animal models of IGF-I deficiency as they often exhibit increased ROS production and decreased NO bioavailability, mimicking the vascular aging phenotype[294]
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But researchers recommended larger clinical trials to not only confirm promising findings, but also to determine ideal dose amounts and if there were any side effects
