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Tirzepatide is a 39amino acid dual incretin receptor agonist that activates both GLP1 and GIP receptors, enhancing glucosedependent insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite [1] [2]
However, it also presents new challenges
Yu H, Mistry J, Nicar MJ, Khosravi MJ, Diamandis A, Van Doorn J et al
Considered to have a placebo-like safety profile in clinical trials
More long-term trials are needed, but the evidence we do have suggests that taking semaglutide for two years has various health benefits
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