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The progressive degeneration of neuronal cells that accompanies the decline of memory and other cognitive functions in subjects with Alzheimers disease is associated with an intracellular aggregation of Tau fibrils, an extra-neuronal accumulation of b-amyloid peptides into senile plaques, and an oxidation-reduction (redox) imbalance of complex etiology
Skeletal muscle free carnitine content is also reduced during moderate intensity exercise when muscle glycogen content is elevated
Hartwig FP, Smith GD, Bowden J
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