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The most common adverse effect related to skin are site injection reactions, effluvium, and allergic reactions including acute urticaria and angioedema [5]

One of its primary roles is fueling the mitochondria, the powerhouses of the cells

[28] This raises the possibility that this extracellular glutamate plays an "endocrine-like" role as part of a larger homeostatic system

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Although these ROS are transient, they can interfere with cell function, including that of HUVECs, and delay wound healing, especially in chronic wounds with severe oxidative stress, where this damage is more severe