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Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

The method involved intracellular oxidation of non-fluorescent dye dihydrorhodamine-(DHR)-123 to the fluorescent rhodamine-123 (R123) caused by free radicals and hydrogen peroxide

BPC 157 10 g/kg, intraperitoneally or per-orally, was given with l-NAME (5 mg/kg intraperitoneally) and/or L-arginine (100 mg/kg intraperitoneally) and it maintained its original beneficial effect

This screening ensures baseline pancreatitis status is established before therapy initiation

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