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Research published in Frontiers in Pharmacology demonstrated that TCTP-PTD variants and penetratin analogs significantly improved the nasal absorption of exendin-4 and GLP-1 in both normal and diabetic mouse models

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It is also why multi-filer situations are among the most analytically complex in the generic industry: when multiple applicants file P.IV certifications against the same patent on the same day, the 180-day exclusivity is shared among all same-day filers, substantially diluting its value

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