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It was a small-scale study (just 15 participants) whose researchers received their liposomal NMN from a company that sells it (a potential introductory point for bias)
Ma et al, 2003b
The results of chromatin immunoprecipitation assays demonstrated that DRD2 activation increases Gclc and Gclm expression by enhancing the binding of Nrf2 to their gene promoters (Fig
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Hence, targeting both of them simultaneously might be a promising approach to hinder therapeutic resistance by blocking all potential alternative routes
