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Cancer-associated adipocytes exhibit phenotypic changes including secretion of the lipids, inflammatory cytokines, and an imbalance in adipokine signaling pathways, such as the upregulation of leptin and downregulation of adiponectin, which promote tumor proliferation and invasion (123)

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Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites

These genes are LRRK2 (leucine-rich repeat kinase 2), alpha synuclein, parkin, VPS35 (vacuolar protein sorting 35), DJ-1 (protein deglycase) and PINK1 (phosphatase and tensin homologue-induced kinase1)

Sikiric P, Seiwerth S, Rucman R, et al