It should be used with caution in children & adolescents (aged 6 months to 18 years) and in elderly patients (aged above 65 years) after consulting the doctor
Boca Raton, Florida: CRC Press
Chemical Information CAS Number 2023788-19-2 Purity 99%+ HPLC Verified Molecular Formula C 225 H 348 N 48 O 68 Molar Mass 4813.5251 g/mol Form Factor Lyophilized Powder Synonyms Research Applications Metabolic Research: GLP-2 (TZ) is investigated as a dual GIP/GLP-1 receptor agonist in experimental metabolic models
What they found (summary): MC1R: melanogenesis, pigmentation, anti-inflammation MC2R: ACTH receptor in the adrenals (Melanotan II does not act) MC3R: energy, cardiovascular function, anti-inflammation MC4R: appetite (central control), sexual function, autonomic regulation MC5R: exocrine glands (sebaceous, lacrimal, salivary) Mutations in MC4R are the most common monogenic cause of obesity in humans Why it matters: Cones review article is the reference article for all of melanocortin pharmacology
Hwang SY, Oh H, Rhee MY, Kang S, Kim HY