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Supplementary material The Supplementary Material for this article can be found online at: References 1 ChenJ.WangM.JoyceA.DeFrancoD.KavosiM.XuX.et al (2014)
Both methods were found to be equally effective in normalizing serum vitamin B12 levels and reducing markers of deficiency such as methylmalonic acid (MMA) and homocysteine (Hcy)
According to USP commentary, preservative-free preparations are often preferred for direct injection into sensitive tissues
The dosing regimen may depend on the specific patient population, with low-dose, long-term supplementation possibly being sufficient in healthy individuals, whilst patients with end-stage renal disease probably need higher dosages and ideally in combination with folate
These results help you and your doctor figure out if your issue is likely dietary or something more complex
