Flowchart from BSH Cobalamin and Folate Guidelines stichtingb12tekort.nl/weten
Ranard, K.M., Kuchan, M.J., Bruno, R.S., Juraska, J.M., Erdman, J.W., 2020
Patients taking insulin or sulfonylureas alongside any incretin-based therapy should be aware of an increased risk of hypoglycaemia, and dose adjustments may be required
The maximum documented refrigerated shelf life for compounded semaglutide from pharmacies with the most rigorous stability testing programs is approximately 120 days (about 4 months) when stored continuously at 2-8 degrees Celsius in the original sealed vial
The SURMOUNT-1 DXA substudy found that tirzepatide produced a 33.9% reduction in fat mass and a 10.9% reduction in lean mass over 72 weeks, with approximately 75% of total weight lost coming from fat and 25% from lean mass