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Glucagon like peptide-1 (GLP-1) is the natural ligand of GLP-1R

FEBS Lett 427 :1520

Evaluating Side Effects and Safety Profiles Both peptides exhibit a safety profile that warrants careful consideration

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In selected patients, especially those with obesity, diabetes, metabolic syndrome or increased cardiovascular risk, GLP-1 receptor agonists may be worth considering or discussing as part of overall patient management. For more information: Beata Jastrzb-Mikiewicz , MD, PhD , is a dermatologist and venereologist at Wrocaw University of Science and Technology in Poland