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A key driver of this process is insulin resistance, which affects both hepatic and peripheral tissues, creating a metabolic environment that simultaneously promotes hyperglycemia and hepatic steatosis through selective pathway activation

It is estimated that more than 2.3 million people worldwide have been diagnosed with MS

[8] Metformin with GLP-RA & Long-term Outcomes: In patients with T2D, dual therapy with metformin and GLP-RA has demonstrated a 39% lower incidence of adiposity-related cancers (HR 0.61) and a 67% reduction in all-cause mortality (HR 0.33) compared to DPP-4 inhibitor use, with effects most pronounced in younger people with obesity

For example, one study found that brain volume and attention improved in people with bipolar who took liraglutide (and stayed on their regular psychiatric medications)