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Understanding the science and safety considerations is essential for informed decision-making
Thyroid hormone therapy for obesity and nonthyroidal illnesses: a systematic review
Compounded medications carry additional risks
In a Mayo Clinic study presented at an annual meeting of the Endocrine Society in July 2025, researchers found that, over 18 months, 40 postmenopausal women who combined the GLP-1 drug tirzepatide (used in Mounjaro and Zepbound) with hormone therapy lost an average of 17 percent of their body weight
It is generally limited to clinical trial or approved research channels
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