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The study did not meet the primary endpoint of change on a measure of how much sugar the brain uses for energy, but it showed that patients on the drug had nearly 50% less shrinking in parts of the brain that control memory and learning and that treated participants had a slightly slower decline in cognitive function
2 They typically originate in the spine or paraspinal soft tissue, although this particular case report presents one within the carotid space
Tirzepatide combines appetite suppression with enhanced metabolic action and has demonstrated higher average weight loss than semaglutide alone in head-to-head studies, making it our preferred option for patients seeking maximum results
A Nature genetics paper (April 2026, n=27,885) identified GLP1R and GIPR variants predicting response and side-effect risk
