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Cancer Epidemi- ology
Why metformin is different The body does not metabolize metformin at all, and there is no interaction with CYP3A4
It does not act as a stimulant
For example, the P5 exenatide analogue is biased to reduce the recruitment of -arrestin, resulting in better long-term hypoglycemic effects than those shown by exenatide, under the precondition that P5 has less cAMP activity
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