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reported that downregulated IIS increased tau phosphorylation, promoted GSK activation, and decreased insulin receptor substrate-1 (IRS1), phospho-Akt, drebrin, and postsynaptic density (PSD95) resulting in cognitive impairment in the HFD model [156]

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By naturally regulating appetite, enhancing insulin secretion, and slowing gastric emptying, this hormone and its synthetic agonists offer a dual benefit for those looking to manage both diabetes and weight

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For example, alpha-fetoprotein (AFP), miR-122, and circulating TERT promoter mutations are biomarkers used for diagnostic screening of HBV-related HCC (Trung et al., 2020)