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or your symptoms have not improved, have returned, or have changed despite treatment
FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes
Intramuscular injections (IM): Faster absorption, slightly harder to self-administer
Experts explain these safety points in clinical guidance about B12 usage
W., Waters, M
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