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Moreover, an abundance of prior studies have underscored the protective effects of Nrf2/HO-1 pathway activation against renal oxidative damage in diabetic models (61-63)

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Kent, Joseph S

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Dietary modifications are essential, including encouraging patients to consume small, frequent meals to reduce gastric distension and improve emptying, adopting a low-fiber, low-fat diet to minimize delays in gastric emptying, and incorporating liquid nutrients that are easier to digest

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Cellular thiols, hydroquinones and catecholamines can undergo redox reactions and contribute to intracellular ROS production as well

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In most people, these effects likely balance out, but individuals with pre-existing blood sugar concerns should monitor their glucose levels more frequently during the initial weeks of combination use

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