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The 2010 RCT of 42 hirsute PCOS women showed measurable testosterone reduction and subjective hirsutism improvement on twice-daily spearmint tea (Grant 2010), and the earlier clinical trial established the anti-androgenic mechanism (Akdoan et al

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This mechanism is supported by Pickarts foundational research on GHK-Cu and tissue remodeling, which established the peptides role in accelerating wound closure and improving the structural quality of regenerated tissue

Nephropathy is aggravated by fatty acids in diabetic kidney disease through tubular epithelial cell necroptosis and is alleviated by an RIPK-1 inhibitor