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Mente, A
Efficacy in hard populations tells you what it will do
The first dual GIP/GLP-1 receptor agonist, NNC0090-2746 (also known as RG7697, RO6811135, or MAR709), is a 40-amino acid peptide acylated with a C16:0 fatty acid to lysine residue at position 40 [ Figure 2 , Table 1 ]
Due to the defined dual-peptide structure and stable analytical profile, this blend is frequently referenced in experimental peptide research models
In a canine model of sepsis induced by intravenous injection of 0.2 mg/kg LPS from E
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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