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While pancreatic -cells are the principal therapeutic target, GLP-1Rs are widely expressed in -cells, exocrine pancreas, intestinal mucosa, renal tubules, pulmonary epithelium, selected brain nuclei, and the cardiac sinoatrial node
This creates a connected defense network where glutathione acts like a central hub that maintains the entire antioxidant system
EClinicalMedicine, 93, 103796
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