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This effect comes from the brain rather than just the blood vessels

All of these effects could enhance the clearance of glucose from the bloodstream

Chuljerm H, Maneekesorn S, Somsak V, Ma Y, Srichairatanakool S, Koonyosying P

A primary cause is the medications effect on gastric motility, leading to slower digestion and a sensation of fullness that may reduce overall caloric intake

Metallothioneins, the most important intracellular copper storage proteins, are also upregulated by GHK-Cu, providing an additional protective mechanism against copper-induced toxicity