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Suitable for : All skin types Targets : Uneven skin tone, dull skin, pigmentation, melasma, acne marks, PIH Key ingredients : kojic acid, glutathione, niacinamide Pregnancy safe Not suitable for people with fungal acne Formulated without mercury, steroids, dyes, fragrances and preservatives known to cause adverse skin reactions
Key physiological features include: Filaggrin gene mutations , leading to a compromised skin barrier and increased transepidermal water loss Th2-skewed immune response , with elevated IL-4, IL-13, and IgE levels Colonization with Staphylococcus aureus , often contributing to inflammation and secondary infection Heightened mast cell activity , promoting pruritus and dermal reactivity This pathophysiology supports a dual treatment approach: barrier repair and inflammation modulation , often in combination with antimicrobial or immunosuppressive strategies
It plays a crucial role in detoxification and protecting cells from oxidative stress
Clin Chest Med