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The trial included 60 adult participants (mean age approximately 49) who had clinical follow-up with labs every 2 months for up to 2 years, with some withdrawing early due to spontaneous remission, indication for definitive therapy (e.g., thyroidectomy or radioiodine), or an intolerance to the treatment
Patient support programs and talking with healthcare providers may help people find options to continue treatment when needed
With significant or rapid weight loss, particularly when driven by GLP-1 drugs, several mechanisms converge: Loss of underlying fat volume removes structural support Collagen and elastin fibres become stretched and fragmented Speed of weight loss outpaces skin contraction While some rebound occurs naturally, significant laxity can be permanent, especially after large weight reductions
You could start by consulting a dermatologist or another healthcare provider
Taking magnesium in the evening can support sleep quality, which many GLP-1 users struggle with due to medication-related insomnia
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