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Nrf2 is a transcription factor that regulates the expression of antioxidant and detoxification enzymes, such as glutathione S-transferases (GSTs), SOD, and catalase
Patients typically notice improvements in fasting blood glucose within the first few weeks, while full effects on HbA1c become apparent after 12-16 weeks
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While it is plausible biologically and supported by clinical trials that weight loss alone would decrease breast cancer risk, GLP-1 agonists are likely working through other pathways
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