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Fertility preservation TRT suppresses sperm production and eventually leads to little to no sperm in the ejaculate

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Frequency of epileptiform EEG abnormalities in a sequential screening of autistic patients with no known clinical epilepsy from 1996 to 2005

Two registered trials exist: a Phase 1 safety and pharmacokinetics study (NCT02637284) with no posted results, and a Phase 2 hamstring-strain trial (NCT07437547) still recruiting

Calcidiol can also be hydroxylated at the 24 position by a specific vitamin D 3 -24-hydroxylase (encoded by the CYP24A1 gene) in the kidneys, intestine, placenta, and cartilage which are all tissues that express the VDR