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Important safety information includes a boxed warning for risk of thyroid C-cell tumors, with contraindications in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Common side effects Most side effects involve the stomach, tend to be mild to moderate, and usually ease as your body adjusts: Nausea Diarrhea Vomiting Stomach pain, bloating, and constipation Indigestion, heartburn (GERD), and burping Headache, dizziness, and tiredness Reduced appetite and weight loss Low blood sugar, mainly when taken with a sulfonylurea or insulin Serious side effects Get medical help right away if you notice any of these: Who should not take semaglutide

Dietary reassessment is essential

Semaglutide first marketed as Ozempic for diabetes and later as Wegovy for obesity is heralded as a breakthrough drug for its ability to promote an average loss of 15% to 20% of a person's body weight

Mineral absorption presents a more complex picture