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Weber EJ, Chapron A, Chapron BD et al (2016) Development of a microphysiological model of human kidney proximal tubule function
You may also be more likely to develop vitamin B-12 deficiency if you have: Atrophic gastritis, in which your stomach lining has thinned Pernicious anaemia, which makes it hard for your body to absorb vitamin B12 Conditions that affect your small intestine, such as Crohns disease, celiac disease, bacterial growth, or a parasite Immune system disorders, such as Graves disease or lupus Been taking certain medications that interfere with the absorption of B12
Each way affects how fast the B12 is absorbed and how often shots are needed
All of these situations require a solvent that carries zero microbial load and acts as a preventative against microbial growth
That gap is the joint line
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