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The clinical trial data showed that using a lower starting dose (2 mg vs 4 mg initial) significantly reduced the incidence and severity of these symptoms
In comparison, a prospective trial investigating oral supplementation of mixed tocopherols and -lipoic acid in stage 3 and 4 CKD patients has revealed disappointing results
It is also possible for urine odor to change because of infection, especially urinary tract infections (UTIs)
This makes it a triple agonist, sometimes called a "triple G" agonist for targeting all three pathways
This is why a formal economic analysis is valuable
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