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Given the ease in accessing blood samples, blood-based biomarkers are frequently used as measures of REDOX state (e.g., refs
They work in complex ways that were still learning about
[1] [2] When neurological symptoms are present such as paraesthesia, numbness, balance problems, or cognitive changesmore aggressive treatment is required
Because NNMT occupies a central position within nicotinamide methylation pathways, it has become an important target for investigations involving enzyme regulation, methyl-donor utilization, cofactor-associated signaling networks, and methyltransferase pharmacology
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