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doi: 10.1038/s41413-022-00237-6 25 ZajcACzarneckaARutkowskiP
The diagnostic utility of OSMs goes beyond simple identification, extending to the monitoring of disease progression and assessing the effectiveness of treatment interventions
Study discontinuation rates were under 2% across all recorded protocols
That is one of the reasons, as the NICE guideline says, that we need to adjust treatment to the patients symptoms, not do a blood test or prescribe a one-size-fits-all dose
Possibly because NAC does not cross the blood-brain barrier well enough, the patient eventually succumbed to a novel and rapid onset of CNS disease
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